How many U.S. overdose deaths occurred in 2024?

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CDC provisional data showed approximately 80,391 drug overdose deaths in 2024, down from 110,037 in 2023—a 26.9% decline. This marks the lowest annual total since 2019 and the largest single-year decrease ever recorded. The decline follows years of escalation: deaths peaked near 110,000 in 2022, fell slightly in 2023, then plummeted in 2024. Fentanyl-involved deaths dropped from over 76,000 in 2023 to just over 48,000 in 2024. However, deaths involving stimulants like methamphetamine increased from 29,456 to 37,096, showing the crisis hasn't ended—it's shifting.

How many U.S. overdose deaths occurred in 2024?

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